Scientific Program

Conference Series Ltd invites all the participants across the globe to attend 30th International Congress on Vision Science and Eye Barcelona, Spain.

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Scientific Program Day 1

Day 1 :

Keynote Forum

Khaled G Abu Eleinen

Cairo University, 2Fayoum eye hospital, Egypt

Keynote: Sutureless Wide Incision Cataract Surgery Using Viscoexpression in Brown Mature Senile Cataract
Biography:

Khaled G Abu Eleinen is a renowned Ophthalmology Professor. Khaled G Abu Eleinen is working in Department of Ophthalmology, Faculty of Medicine, Cairo University, Cairo, Egypt and Department of Ophthalmology, Fayoum eye hospital, Fayoum, Egypt . He publishes many articles in reputed journals.

Abstract:

Purpose: To assess visual acuity, surgically induced astigmatism, endothelial cell loss, operative time and complications of sutureless wide incision cataract surgery in brown mature senile cataract using viscoexpression. Settings: Tertiary care ophthalmic unit, Egypt, over the last 8 years from 2012 to January 2020 Methods: Retrospective, interventional case series that included 472 eyes in 413 patients with brown, mature senile cataract that deemed risky for phacoemulsification. Wide and long superior sclerocorneal tunnel incision with straight posterior border was constructed. After anterior capsulotomy, the nucleus was rotated into the anterior chamber (AC). The nucleus was expressed by injection of ophthalmic viscosurgical device (OVD) into the AC followed by irrigation aspiration and intraocular lens implantation. Results: patients ages ranged from 57 to 93 years, (Mean 74.6 +5.3) Ten weeks after surgery, decimal visual acuity of 0.5 or better was achieved by 80.6% of cases as best corrected and by 67.6% of cases as uncorrected visual acuity. Flattening of the vertical meridian by 1 diopter or less was noted in 88.7% of eyes. Average loss of endothelial cells was 13 % (P < 0.0001 paired samples T-test) in 104 eyes that underwent specular microscopy. Average duration of the operation was 11.2 +3.5 minutes. Postoperative hyphema was recorded in 6 eyes (1.27%). Significant corneal edema was noted in 3 eyes (0.64%). Vitreous loss occurred in 5 eyes (1.06%). Postoperative uveitis with residual posterior synechiae developed in 4 eyes (0.85%). Early postoperative rise of tension was recorded in 10 eyes (2.1%). Decentration of IOL was recorded in 2 eyes due zonule dehiscence (0.42%) that required replacement with Ac-IOL. Conclusions: Sutureless wide incision cataract surgery (SWICS) was a safe alternative to the classic ECCE for removal of brown mature senile cataract where phacoemulsification appeared hazardous. It spared time and reduced surgically induced astigmatism related to wound suturing.

Keynote Forum

Rohit Sharma

University Hospitals Derby and Burton, UK

Keynote: Eyedrop questionnaire- Glaucoma, ocular surface & preservatives
Biography:

Rohit Sharma is working in University Hospitals Derby and Burton
UK
 

Abstract:

Purpose: Preservatives found in topical eye drops for glaucoma treatment have various side effects which manifest as ocular surface disease (OSD) with symptoms such as dry, irritated red eyes and watering. Various studies have compared outcomes between those who use non-preservative free (NPF) drops and preservative free (PF) drops and have shown positive results for the latter including less OSD symptoms and better adherence. One barrier to using PF drops is cost; the cost of PF drops sometimes being x10 that of NPF drops. This study investigated whether there were significantly positive outcomes to justify the cost of PF drops.

Methods:A questionnaire was designed for patients to self-report theirsymptoms, treatment and complete OSDI (Ocular Surface Disease Index) and SANDE (Symptoms Assessment in Dry Eye) scores.

Results:A total of 71 patients responded. 40 patients (56%) had glaucoma and of this,9 (23%) used PF drops, 16 (40%) said they did not. The rest (15) were unsure or did not answer. All patients who used PF said it helped with around half saying they were easier to use. However, NPF drops had better SANDE scores with higher proportion of users placing the severity and frequency of symptoms on the ‘Rarer’ side of the scale compared to PF drops. Furthermore, NPF drop users also reported lower OSDI scores (median 7, average 10) correlating with better symptoms compared to PF drops (median 20, average 19). In4 PF users and 1 NPF user, drops made their glaucoma symptoms worse.

Conclusions:This study found that although all patients using PF drops reported they had helped, they contradictorily reported worsening symptoms both through free text comments and through OSDI and SANDE scores. These outcomes were worse when compared to NPF drop users. Larger multicentre trial is urgently required to establish whether the cost benefit of PF drops is completely rationalised.

Keynote Forum

Omar Saeed

Ohio University Heritage College of Osteopathic Medicine, Athens, OH, United States of America

Keynote: Examining Incidence of Acute Angle Closure Glaucoma in U.S. Emergency Departments
Biography:

Omar Babar Saeed is working in Ohio University Heritage College of Osteopathic Medicine, Athens, OH, United States of America

Abstract:

Introduction:
Acute angle closure glaucoma (AACG) is a medical emergency that presents with blurred vision, painful red eye, headache, nausea, and vomiting. AACG presents from a rapid rise in the intraocular pressure in the eye most common due to a sudden blockage in the drainage of aqueous fluid. Strong risk factors associated with AACG include female gender, hyperopic vision, previous AACG, advanced age and Inuit and Asian ethnicity. The purpose of this study was to identify additional factors that contribute to AACG. 
 
Methods:
The 2015 Nationwide Emergency Department Sample (NEDS) was used to model the incidence of AACG in U.S. emergency departments based on various patient demographic and socioeconomic data. There were 5,241 weighted cases (0.0046%) of acute angle closure glaucoma in the 2015 NED dataset.
 
Results:
Results of multivariate logistic regression indicate that older patients, particularly patients 65-84, were significantly more likely to present to the ED with acute angle closure glaucoma (OR: 21.036, CI: 3.104;142.547). Males were significantly less likely to present with acute angle closure glaucoma than females (OR: 0.614, CI: 0.461; 0.817). There were no significant differences based on payer or median household income. While no significant differences were found based on the presence of the comorbidity heart failure, patients without hypertension or diabetes were significantly more likely to experience acute angle closure glaucoma than patients with hypertension or diabetes. 
 
Conclusions
The results of this study provide further evidence on the risk factors that contribute to AACG. 
Interestingly, those with hypertension or diabetes were less likely to experience AACG. A potential protective mechanism of these comorbidities can be explored further in future analyses.  
 

Keynote Forum

Muhammed Omar Qadir

West Midlands, UK

Keynote: Outcomes of surgical management of intermittent exotropia in apaediatric age group - a retrospective study in a multi-ethnic metropolitan population
Biography:

Muhammed Omar Qadir is currently undergoing his training in Ophthalmology in the West Midlands region in the United Kingdom. He is a keen surgeon who has a particular interest in surgical outcomes with recent conference submissions related to surgical outcomes and complication rates. He is also interested in the evolving challenges of surgical training in the UK and has recently published a review article regarding this in Eye. Teaching and training remain a passion of his and he is particularly interested in the role of simulation to improve training. 

Abstract:

Statement of the Problem: Intermittent exotropia is one of the most common types of strabismus in children especially in Asian and South Asian populations. The prevalence of exotropia in this group has been estimated to range from 7-18.5X higher than esotropia. Spontaneous resolution is rare and if neglected may lead to loss of BSV and negative psychosocial consequences. We aim to assess and evaluate the outcomes of surgical management for intermittent exotropia at a unit in Birmingham (UK), a metropolitan area unique for its high non-White ethnic population (43%), the majority of who are Asian/South-Asian.
Methodology. Retrospective case notes review of all patients diagnosed with intermittent exotropia who underwentstrabismus surgery in 2019-2020 by two paediatric ophthalmology consultants using two different surgical approacheswith a 3 month follow up. Measures included preoperative and postoperative visual acuity and stereopsis, surgical indications, near and distance strabismus angle with refractive correction, type of surgery performed and parental satisfaction at follow up. 
Results.19 children underwent surgery during this period with a mean age of 7 range (4 to12). 18 patients had surgery for functional reasons and one for cosmetic. 2 patients recovered BSV where previously Frisby negative,remaining patients maintained BSV. The mean preoperative near and distance exodeviation was 30.16 PD and 34.47 PD respectively. The mean postoperative near and distance exodeviation 1.53PD & 5.16 PD respectively at 3 months. 2 patients developed suture granulomas which resolved with steroid drops post-operatively.  No significant difference between the two surgical techniques was noted. In all cases, parents were satisfied with the results.
Conclusion & Significance:
Outcomes in our multi-ethnic population have been excellent in terms of improvement in exodeviation and maintenance of BSV.  Long-term follow up is required to see how many patients will show evidence of recurrence requiring reoperation and whether ethnicity impacts this.
 

Keynote Forum

Musab K. Alaql

Medicine, Jouf University, Sakaka, SAU

Keynote: Treatment of Vogt-Koyanagi-Harada Disease
Biography:

Musab K. Alaql is a renowned ophthalmology Student in Saudi Arabia doing his MBBS from the Jouf University, Saudi Arabia. Musab K. Alaql is working in Department of Ophthalmology, Jouf University, Saudi Arabia. He publishes many articles in reputed journals.          

Abstract:

Vogt-Koyanagi-Harada (VKH) disease is a T-cell-mediated autoimmune inflammatory disease characterized by granulomatous panuveitis with a variety of other systemic manifestations. A 29-year-old man referred with a two-week history of pain, redness, photophobia, and blurring of vision of the right eye. The patient reported a history of tinnitus and vertigo. Ocular examination revealed that the visual acuity was hand movement oculus dextrus (OD) and 1.0 oculus sinister (OS), slight periocular depigmentation in the right eye, iris bombe in the right eye, sunset glow sign similar to Dalen-Fuchs nodules of multifocal choroiditis in the right eye, reduced fovea reflex/subtle macular edema in the right eye, and normal anterior and posterior segment OS. The patient underwent a series of investigations and treatments, including corticosteroids, cyclosporine, antibiotics, and other local eye drugs. Surgical treatment included scheduling intravitreal ranibizumab for the right eye. Outcomes included improved general health conditions and improved visual condition (visual acuity improved to 0.8 OD). The combined therapy of immunosuppressive drugs with steroids was effective in improving visual impairment.
 
Categories: Ophthalmology
Keywords: autoimmune, uveitis, systemic, granulomatous
 

Keynote Forum

Isham Alzoub

University of Tehran,Iran

Keynote: Prediction of environmental indicators in land leveling using artificial intelligence techniques

Time : 13:10-13:35

Biography:

Isham Alzoub, University of Tehran,Iran

Abstract:

Land leveling is one of the most important steps in soil preparation and cultivation. Although land leveling with machines require considerable amount of energy, it delivers a suitable surface slope with minimal deterioration of the soil and damage to plants and other organisms in the soil. Notwithstanding, researchers during recent years have tried to reduce fossil fuel consumption and its deleterious side effects using new techniques such as; Artificial Neural Network (ANN),Imperialist Competitive Algorithm –ANN (ICA-ANN), and regression and Adaptive Neuro-Fuzzy Inference System (ANFIS) and Sensitivity Analysis that will lead to a noticeable improvement in the environment. In this research effects of various soil properties such as Embankment Volume, Soil Compressibility Factor, Specific Gravity, Moisture Content, Slope, Sand Percent, and Soil Swelling Index in energy consumption were investigated. The study was consisted of 90 samples were collected from 3 different regions. The grid size was set 20 m in 20 m (20*20) from a farmland in Karaj province of Iran. The aim of this work was to determine best linear model Adaptive Neuro-Fuzzy Inference System (ANFIS) and Sensitivity Analysis in order to predict the energy consumption for land leveling. According to the results of Sensitivity Analysis, only three parameters; Density, Soil Compressibility Factor and, Embankment Volume Index had significant effect on fuel consumption. According to the results of regression, only three parameters; Slope, Cut-Fill Volume (V) and, Soil Swelling Index (SSI) had significant effect on energy consumption. Using adaptive neuro-fuzzy inference system for prediction of labor energy, fuel energy, total machinery cost, and total machinery energy can be successfully demonstrated.
In comparison with ANN, all ICA-ANN models had higher accuracy in prediction according to their higher R2 value and lower RMSE value. The performance of the multivariate ICA-ANN and regression and artificial neural network and Sensitivity analysis and Adaptive neuro-fuzzy inference system (ANFIS) model was evaluated by using statistical index (RMSE, R2 )). The values of RMSE and R2 derived by ICA-ANN model were, to Labor Energy (0.0146 and 0.9987), Fuel energy (0.0322 and 0.9975), Total Machinery Cost (0.0248 and 0.9963), Total Machinery Energy (0.0161 and 0.9987) respectively, while these parameters for multivariate regression model were, to Labor Energy (0.1394 and 0.9008), Fuel energy (0.1514 and 0.8913), Total Machinery Cost (TMC) (0.1492 and 0.9128), Total Machinery Energy (0.1378 and 0.9103).Respectively, while these parameters for ANN model were, to Labor Energy (0.0159 and 0.9990), Fuel energy (0.0206 and 0.9983), Total Machinery Cost (0.0287 and 0.9966), Total Machinery Energy (0.0157 and 0.9990) respectively, while these parameters for Sensitivity analysis model were, to Labor Energy (0.1899 and 0.8631), Fuel energy (0.8562 and 0.0206), Total Machinery Cost (0.1946 and 0.8581), Total Machinery Energy (0.1892 and 0.8437) respectively, respectively, while these parameters for ANFIS model were, to Labor Energy (0.0159 and 0.9990), Fuel energy (0.0206 and 0.9983), Total Machinery Cost (0.0287 and 0.9966), Total Machinery Energy (0.0157 and 0.9990) respectively, Results showed that ICA_ANN with seven neurons in hidden layer had better.”

 

Keynote Forum

Dongyu Guo

Department of Ophthalmology, Zhejiang University School of Medicine Hangzhou, Zhejiang, China

Keynote: Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS-CoV-2 infection
Biography:

Dongyu Guo is working as Department of Ophthalmology, Zhejiang University School of Medicine Hangzhou, Zhejiang, China
 

Abstract:

Objective:This study aimed to assess the presence of novel coronavirus in tears and conjunctival secretions of SARS-CoV-2 infected patients.
Methods: A prospective interventional case series study was performed, and 30confirmed novel coronavirus pneumonia (NCP) patientswere selected at the First Affiliated Hospital of Zhejiang University from January 26, 2020 to February 9, 2020. At an interval of 2–3 days, tear and conjunctival secretions were collected twice with disposable sampling swabs for reverse transcription polymerase chain reaction (RT-PCR)assay.
Results:21 common type and 9 severe type NCP patients were enrolled. Two samples of tear and conjunctival secretions were obtained from the only one patient with conjunctivitis yielded positive RT-PCR results. 58 samples from other patents were all negative.
Conclusion:We speculate that SARS-CoV-2 may be detected in the tears and conjunctival secretions in NCP patients with conjunctivitis.
 

Keynote Forum

Rohit Sharma

University Hospitals Derby and Burton, UK

Keynote: Acute Glaucoma with Citalopram.
Biography:

Rohit Sharma is a renowned Consultant Ophthalmic Surgeon University Hospitals Derby and Burton, UK gaining his MBBS MS MRCSEd Edinburgh FRCOphth London. Rohit Sharma is working in Department of Ophthalmology, University Hospitals Derby and Burton, UK. He publishes many articles in reputed journals.

Abstract:

Although there is no mention of acute glaucoma on the list of side effects of citalopram in some patient information leaflets, here have been previous published case reports on association of citalopram and other ssr is (selective serotonin reuptake inhibitirs) with acute glaucoma. It is the most severe ssr is related ocular complication. 
Risk factor: race-asianorigin, hyper metropia, family history, female gender, age and shallow anterior chamber. Mechanism of ssri induced acute glaucoma is not clear.
 
An elderly lady with no previous history of glaucoma presented with acute headaches, bilateral ocular pain, photophobia ,worsening vision and fixed dilated pupils. With bilateral raised intra ocular pressures she was initially treated with systemic acetazolamide, ocular hypotensives  then bilateral yag iridotomy. Subsequently  stopped acetazolamide and pilocarpine.she returned with worsening vision and significantly raised iops this time. Her ultrasound b-scans remained unremarkable (though sometimes they can show typical findings).she was discussed with glaucoma specialist (rs) who asked for a full drug history and who stopped the oral citalopram subsequently. Her IPOS normalized improving her symptoms and vision markedly .
 
This patient had been seen a few times earlier , however, a comprehensive drug history was not obtained earlier. A low threshold for drug induced causes of bilateral acute glaucoma, including this as side effect in pils (patient information leaflet) and detailed ophthalmic examination including gonios copy should be carried out even in the presence of patent iridotomies in high risk patients. Warning advice and counselling to the patients should be given.
 
 

Keynote Forum

Damaris Hodelin Fuentes

Ophthalmology Researcher, Cuba

Keynote: Nutrition and visual diseases
Biography:

Damaris Hodelin Fuentes, MD, Ophthalmology Researcher on General Hospital Dr. Juan B. Zayas Alfonso, Cuba, received the Award to Scientific Worthy 2016 and has a long career as investigator engaged in 24 research projects, most of them as leader, about General Ophthalmology, Neurophthalmology, Bioethics, and Nutrition to the ocular health. Due to her investigations, she has been awarded with the Future Builder Commemorative Stamp and was nominated to the Sciences Academic of Cuba as a Younger Member. She has many publications in national and international journals, and is on the reviewer board of Ophthalmology Research: An International Journal, where has been received the Certificate of Excellence in Reviewing. She is also Associate Editor of Peer Research Nest, and member of the Editorial Board in International Journal of Ophthalmology and Visual Science. She has presented papers in various conferences and has received many awards for the same.

Abstract:

Nutrition has influence in vision. Important nutrients, such as vitamins A, C, D and E, lutein and zeaxanthin have essential function on visual health. The objective of this study is to demonstrate the nutrition´s influence in the beginning or prevention of visual diseases like dry eye syndrome, cataracts and age-related macular degeneration. A search was made in PubMed, Infomed, EBSCO, HINARI, Scielo; using as key words: nutrition, visual diseases, vitamin. Were used 32 articles in Spanish and English languages. The 60% corresponds to the last five years. Trials have reported a prevalence of dry eye syndrome twice higher in females than in males; it´s related with vitamin D deficiency. Trials with vitamin D and omega-3 supplements have shown relief of the illness. Cataract, the principal cause of reversible blindness on the world, it´s related with vitamin C and E deficiency. Vitamin A, lutein and zeaxanthin have influence in age-related macular degeneration. As conclusions, this study gives information about the actual stated of nutrition and its relationship with the beginning or prevention of some visual diseases.